Unlike hyped supplements such as tribulus, that don’t do jack to increase testosterone, the South African herb Bulbine Natalensis works and has been shown in studies to increase testosterone by a whopping 347% and crush estrogen by 35%. This is exactly what you want in an all-natural testosterone booster.
What you do not want is to increase testosterone and have the majority of it convert into estrogen via aromatase enzymes. Estrogen dominance is a big problem right now (the popularity of reality TV is overwhelming proof!) and any steps to increase testosterone should be balanced with controlling excess estrogen for maximum benefit. At the same time you don’t want to drive estrogen too low, as it is a surefire way to kill sex drive, sex function, and mood. The key is balance and an optimal ratio of testosterone to estrogen, which is what Bulbine Natalensis helps provide.
Now when it comes to Bulbine, it is critical that you use the right extract. The highest quality extract on the market is known as ProLensis™. If it is not ProLensis you are wasting your money and time. ProLensis™ is the same extract of bulbine that was used in the studies that proved its efficacy. In addition to the importance of utilizing ProLensis™ it is also critical to have the right dose. More is not better with Bulbine Natalensis and too much can lower testosterone.
How ProLensis™Bulbine Natalensis works
ProLensis™ is a multi-faceted compound in all of the ways it exerts its positive effects on the hormonal balance of the body.
In regards to testosterone, ProLensis™ increases GnRH-LH signalling, and also increases cholesterol in the testes. These distinct processes are important for testosterone synthesis. GnRH, or Gonadotropin-Releasing Hormone, is released from the hypothalamus in the brain. In turn, this stimulates the release of LH, or Luteinizing Hormone, from the pituitary. LH is the hormone that directly stimulates cells (called Leydig Cells) in the testes to release testosterone. Evidence shows that ProLensis™ can stimulate LH 169% compared to study controls.
By enhancing GnRH-LH signalling, ProLensis™ amplifies the process by which testosterone is stimulated, akin to turning up the volume on a stereo.
In cooperation with this, ProLensis™ also elevates levels of testicular cholesterol. Cholesterol is the equivalent of raw material in the testes job of creating testosterone. The cholesterol is taken up into the mitochondria of the testes where it is processed into pregnenolone. From this stage it is converted into sex steroids and glucocorticoids. Due to cholesterol’s status as a raw material, it’s uptake into the testes is the rate-limiting step in sex steroid synthesis. This manifests into a marked increase in testosterone of 347%, as shown in research.
In other words, testosterone creation can only be enhanced if testicular cholesterol levels are elevated. In doing this, ProLensis™ increases testosterone output.
ProLensis™ has also been shown to act as an aphrodisiac. Studies involving mammals given ProLensis™ show a significant increase in frequencies of mount, intromission, ejaculation and ejaculatory latency. This effect is believed to be due to the increase in acid phosphatase (ACPT) in the testes. ACPT is widely distributed in the testes and plays an important role in the physiology of sperm. Increased levels of this enzyme are associated with higher testes output. Researchers believe this effect suggests an enhanced mobilization of carbohydrate and lipid metabolites which are used by the accessory sex structure and/or spermatozoa in the seminal fluid.
ProLensis™ contains phytochemicals that drive the machinery involved in sperm production and sex drive.
In addition to the effects on blood flow to sexual organs that the alkaloid phytochemicals exert, researchers have hypothesized that other constituents of ProLensis™ may act directly on the central nervous system, modulating the action of neurotransmitters. Unbeknown to some, neurotransmitters such as serotonin play a very large role in the complicated science of sex drive.
By influencing neurotransmitters, the bioactive agents present in ProLensis™ further augment the aphrodisiac effect of the extract.
Investigation into ProLensis™ has also demonstrated a marked decrease in estrogen levels in mammalian research models. This decrease is as much as 35% in comparison to study controls. While the researchers do not speculate why this may be the case, they do speculate that this reduction in estrogen may be partly responsible for the increased testosterone.
In summary, ProLensis™ exerts several favorable effects on the hormonal milieu, documented in the table below.
|Testosterone (serum)||↑ 347%|
|Luteinizing Hormone (serum)||↑ 169%|
|Prolactin (serum)||↔ No change|
Stinging Nettle Root
I learned about the benefits of stinging nettle root several years ago from Dr. Jonathan Wright at an anti-aging conference.
Stinging nettle root supports free levels of testosterone and the much stronger DHT (dihydrotestosterone) by unbinding both from SHBG (sex hormone binding globulin). While total testosterone, which represents the total amount of testosterone you’re producing, is important, it is the free testosterone levels that are accessible. The more testosterone that is freed up the more benefit you will derive. Stinging nettle root helps ensures you free up more usable testosterone.
Stinging nettle root has also been shown to support prostate health by lowering overall inflammation and in particular inflammation of the prostate. Stinging nettle root helps block conversion of testosterone into estrogen, which also supports prostate health as excess levels of estrogen can cause prostate inflammation. Similar to Bulbine, stinging nettle root is an excellent stand-alone product for supporting testosterone. Yet, when combined with Bulbine you have an extremely powerful duo.
Mucuna pruriens is an Ayurvedic herb that has been used for centuries to increase libido, energy, optimize blood sugar, mood support, and is well known for its powers as an adaptogen. Mucuna has been shown to increase the neurotransmitter dopamine, which is very important for optimal brain health. Optimal hormone production starts with brain health and optimal levels of dopamine are critical for brain health.
Dopamine is a powerhouse neurotransmitter that provides the boost you need to get out of bed in the morning and take charge of your day. It also plays a big role in sex drive and sexual function. Dopamine controls the sex hormone control center of the brain. Dopamine is also a powerful growth hormone booster and reduces levels of prolactin. Prolactin is a nasty hormone that lowers testosterone levels in men. According to anti-aging expert Dr. Eric Braverman, dopamine is intimately connected to addictive behavior. People with low dopamine levels are often addicted to sources of quick pleasure and easily succumb to addictions. Optimal dopamine levels supports energy, mood, drive, and living a fuller life.
By increasing dopamine, Mucuna supports growth hormone production and reduces prolactin. Mucuna also supports testosterone production by increasing levels of the messenger hormones: Luteinizing Hormone (LH) and Follicle-stimulating hormone (FSH). These messenger hormones signal the natural production of testosterone in men. Mucuna has also been shown to lower high cortisol levels, support healthy blood sugar levels, and increases energy. Mucuna is an all around great supplement that I have been using on and off for many years. It is a fantastic addition!
What happens, when you take a supplement with the right amounts of Bulbine Natalensis, Stinging nettle root, and Mucuna? You ramp up free and total testosterone, reduce estrogen and prolactin, and support dopamine and growth hormone. Optimal levels of testosterone and dopamine play a pivotal role in well-being, mood, motivation, libido, muscle growth, bone health, and heart health. Keeping estrogen in check is vital to get the full benefits of testosterone and also reduce stubborn fat in the pecs, midsection, and lower body.
1. Androgenic activities of Bulbine natalensis stem in male Wistar rats. Yakubu MT, Afolayan AJ. Pharm Biol. 2010 May;48(5):56876.PMID: 20645801
2. Effect of aqueous extract of Bulbine natalensis (Baker) stem on the sexual behaviour of male rats.Yakubu MT, Afolayan AJ.Int J Androl. 2009 Dec;32(6):629-36. Epub 2008 Aug 15.PMID: 18710410 [PubMed – indexed for MEDLINE]
3. Schottner, M., G. Gansser, and D. Spiteller. “Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG).” Planta Med. 63 (1997): 529-32
4. Tripathi YB, Upadhyay AK. Effect of the alcohol extract of the seeds of Mucuna pruriens on free radicals and oxidative stress in albino rats. Phytother Res. 2002 Sep;16(6):534-8.
5. Sharma ML, Chandokhe N, Ghatak BJ, Jamwal KS, Gupta OP, Singh GB, Ali MM, Thakur RS, Handa KL, Rao PR, Jamwal PS, Sareen YK. Pharmacological screening of Indian medicinal plants. Indian J Exp Biol. 1978 Feb;16(2):228-40.
6. Rajeshwar Y, Kumar GPS, Gupta M, Mazumder UK. Studies on in vitro antioxidant activities of methanol extract of Mucuna pruriens (Fabaceae) seeds. Eur Bull Drug Res. 2005;13:31
7. Lignans bind to sex hormone-binding globulin (SHBG) Schöttner, M., D. Gansser, and G. Spiteller. “Interaction of lignans with human sex hormone binding globulin (SHBG).” Z Naturforsch C 52 (1997): 834-43. PubMe
8. Shukla KK, Mahdi AA, Ahmad MK, Shankhwar SN, Rajender S, Jaiswar SP. Mucuna pruriens improves male fertility by its action on the hypothalamus-pituitary-gonadal axis. Fertil Steril. 2009 Dec;92(6):1934-40.
9. Shukla KK, Mahdi AA, Ahmad MK, Jaiswar SP, Shankwar SN, Tiwari SC. Mucuna pruriens Reduces Stress and Improves the Quality of Semen in Infertile Men. Evid Based Complement Alternat Med. 2007 Dec 18.
10. Kumar KVA, Srinivasan KK, Shanbhag T, Rao SG. Aphrodisiac activity of the seeds of Mucuna pruriens. Indian Drug. 1994;31:321–7
11. Yamada T, Nakamura J, Murakami M, Okuno Y, Hosokawa S, Matsuo M, Yamada H. Effect of chronic L-dopa administration on serum luteinizing hormone levels in male rats. Toxicology. 1995 Mar 31;97(1-3):173-82.
12. Chihara K, Kashio Y, Kita T, Okimura Y, Kaji H, Abe H, Fujita T. L-dopa stimulates release of hypothalamic growth hormone-releasing hormone in humans. J Clin Endocrinol Metab. 1986 Mar;62(3):466-73.
13. Boyd AE 3rd, Lebovitz HE, Pfeiffer JB. Stimulation of human-growth-hormone secretion by L-dopa. N Engl J Med. 1970 Dec 24;283(26):1425-9.