Can healthy aging be achieved without optimal GH levels?

Growth hormone is a protein-based (191 amino acids) polypeptide hormone produced in the pineal gland in the brain and crucial for repair.
It induces cellular growth, reproduction, and regeneration
According to Dr. Mark Gordon, “healthy aging can’t be achieved with a GH deficiency.”
90% of GH’s properties are for restoration and repair and only 10% growth-Dr. Nick Delgado
Dr. Hertoghe states, “GH makes people more assertive, strong-minded, decisive and calm.” Makes you more resilient and able to handle stress more effectively.
Majority of GH is produced between 8 pm and 4 am
Levels decline by 50% from age 20-60 and then the loss ramps up even more so as we age. Most deficiencies occur from age 40 onwards.

Optimal levels of growth hormone help address the following conditions

Signs of depleted growth hormone levels

Determining optimal GH levels

To determine GH production insufficiency and to qualify for GH therapy most doctors will have you do a glucagon pituitary stimulation test.
IGF-1 levels are also measured as they are more stable than GH in the blood.
It is also important to have binding proteins measured. Binding protein 1-6 (1 protects against heart disease, 3 is a major anti-cancer product) Quercetin can raise it at 250mg to 500mg per day.
Dr. Mark Gordon: Half-life of GH is only 20 minutes. IGF binding protein 3 has a 24-hour half-life. If IGF binding protein 3 is high over 5000 you are making adequate GH even if IGF-1 is low.

Action steps to increase GH

Intense exercise increases GH and levels can stay up for two hours. Even moderate aerobic exercise will boost GH levels.
Weight lifting with a focus on compound exercises will ramp up GH levels as well. Deadlifts, squats, pull-ups, overhead press, kettlebell swings, etc.
Sprinting is excellent for increasing GH and a personal favorite.
A high saturated fat/ high glycemic diet can reduce GH by 30%
Optimal estrogen levels help support optimal GH. If estrogen levels go too low it can have a negative impact on GH. Why AI drugs often lower GH.
You may be able to address GH deficiency by addressing low testosterone and low DHEA
Sleep quality is a must for optimal levels of GH as most GH is produced when we sleep.

Supplements that help with GH

Melatonin improves sleep quality which in turn improves GH levels. 1-6mg per night
Magnesium is a natural muscle relaxant which will also improve sleep quality 500-1000mg per day or 8-12 sprays of Recovery oil two times per day.
5 HTTP at 100-200mg increases serotonin levels and relaxation. Take before bedtime.
Theanine helps with relaxation and anxiety at 500mg to 1 gram.
Zinc at 30mg per day (ZMA, recovery oil)
DHEA before bedtime increases GH. I Prefer DHEA cream for superior absorption and also oral DHEA can be stimulating and not ideal before bedtime. 25-50mg.
Citrulline increases arginine more than arginine and in turn, can increase nitric oxide levels and GH
Glutamine 5 grams before bedtime. Glutamine is also great for gut health.
Vitamin D 5000iu to 15,000iu
Mucuna Pruriens increases dopamine which in turn stimulates GH production. 500mg per day.
Nutrabol (often sold with SARMS) is a secretagogue which stimulates GH production
Secretrophin a supplement designed by Dr. Mark Gordon works well for many to increase GH and binding proteins.

Reference Ranges

Reference range for IGF-1 52-328 ng/dl, Optimal range 250-300ng/dl

Sources and recommended reading

The Hormone solution, Dr. Thierry Hertoghe

Mastering the Life Plan, Dr. Jeffrey Life

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